The Schulman Lab in the Department of Pharmacology at the University of Virginia seeks a Laboratory Specialist – Intermediate to assist investigators with experiments examining the regulation of transcription by members of the nuclear hormone receptor superfamily and exploring links between lipid metabolism and inflammation in several model systems. The individual will conduct daily experimental procedures and must be able to master techniques in molecular biology, physiology, pharmacology and biochemistry. The individual will conduct complex research activities and make decisions according to ethical standards, understand laboratory processes and procedures, and perform data analysis. The incumbent will participate in formulating research methods, suggest options for improving quality, and recommend solutions. They will also oversee the day-to-day operation of projects, confer with PI in developing plans for research projects, discuss the interpretation of results, and help prepare scientific manuscripts for publication. Further, the incumbent will have excellent writing and communication skills, strong organizational and interpersonal skills, the ability to follow instructions, and general laboratory knowledge (e.g., lab procedures, basic safety precautions, how to handle samples and laboratory equipment, etc.).
What You Will Do:
Experimental Work: Isolate RNA. Quantify gene expression by QPCR. Work with mice. Perform flow cytometry experiments. Isolate primary hepatocytes. Participate in formulating research methods. Oversee day-to-day operation of projects. Discuss and interpret results.
Laboratory Maintenance and General Duties: Maintain a clean laboratory area and assist with overall laboratory maintenance. Make buffers and other reagents. Maintain a laboratory notebook. Be available to assist principal investigators as needed.
Ordering and Purchasing: Process purchases for the lab using the UVA Marketplace. Interact with vendors to determine appropriate products. Return damaged or incorrect items.
Learn more about the Schulman Lab: https://pharm.virginia.edu/faculty/primary-faculty/?facbio=1&id=25996
Bachelor's degree or equivalent in biology, chemistry, molecular biology, biochemistry or a related discipline and at least six years of laboratory experience in an academic or industrial laboratory setting (years of related experience may be considered in lieu of a degree).
A master's degree in related field may substitute for required experience.
Documented experience in flow cytometry, particularly the identification and analysis of immune cell populations.
Ability to synthesize information, provide advice and address needs independently.
Knowledge of general lab procedures, basic safety precautions and lab equipment.
Ability to work independently and as part of a team.
Proficiency with computer software, including Microsoft Word, PowerPoint and Excel, is required.
Experience working with rodents and with the isolation of primary hepatocytes from mice is preferred.
Preference will be given to candidates who hold a master's or PhD degree in biology, chemistry or a related science.
This position is restricted and contingent upon the continuation of funding.
Anticipated Hiring Range: $50,000-$55,000 annually
Salary will be commensurate with education, skills and experience.
The selected candidate will be required to complete a background check prior to their first day of employment and a health screening per University policy.
Review of applicants will begin February 4, 2022, and the position will remain open until filled.
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